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CIC 1431 - Mr.

    Clinical Investigation Center – CIC 1431

    The CIC-1431, coordinated by Professor Eric Toussirot, works in close collaboration with the RIGHT unit in the context of clinical studies related to the unit’s research themes. These clinical studies may involve the identification of biomarkers or the development of new biological drugs. The CIC-1431 is also an essential partner, alongside clinical services, for the establishment of patient cohorts.

    To illustrate this partnership around clinical studies and patient cohorts, we can mention the ORLY-Est cohort (more than 1,100 patients, enabling research on CD4 T cell lymphopenia, immune system senescence, and complications associated with kidney transplantation), as well as the cohort of acute leukemias derived from plasmacytoid dendritic cells (BPDCN). For the development of new biological drugs, we can highlight the UCPVax study, a vaccination trial using telomerase-derived peptides in non-small cell lung cancer.

    These clinical studies and cohorts are registered with an NCT number on the website clinicaltrials.gov.

    The RIGHT unit and CIC-1431 jointly coordinate the Bio-Monitoring platform.